Electronic Thesis/Dissertation
 

Investigation of the Cell Labeling Procedure and the Appearance of Monozygotic Twins

Open Access

The origins of pairs of monozygotic twins and higher order multiples, i.e. triplets, quadruplets, etc., have been extensively studied but still little is understood. To gain insight into this event, certain possible cell labeling schemes that model an organism’s development are analyzed. The phenomenon of quadruplet twins is exposed during the process. We predict that monozygotic quadruplets are not really quadruplets but instead are two pairs of monozygotic twins where the pairs slightly differ. From the considered models, the probability of monozygotic twins is found to be (1/2)K, and we discover from our analysis that the probability of monozygotic quadruplets, or triplets in the case of the death of an embryo, is (1/8)K, where K is a species-specific integer representing the number of pairs of homologous chromosomes. This investigation into twinning provides a foundation for understanding the process of cell development through which the cell development mechanism is established. The failure of the internal cellular clock from this mechanism may play an important role in cancerogenesis. The parameter K may determine cancerization with a probability threshold that is approximately inversely proportional to the Hayflick limit, so exposure to small levels of ionizing radiation and chemical pollution may not produce cancer.

Author Language Keyword Date created Type of Work License
  • All rights reserved
Rights statement GW Unit Degree Advisor Committee Member(s) Persistent URL

Notice to Authors

If you are the author of this work and you have any questions about the information on this page, please use the Contact form to get in touch with us.

Thumbnail Title Date Uploaded Visibility Actions
Preview of Jim_gwu_0075A_12823.pdf Jim_gwu_0075A_12823.pdf 2018-01-16 Open Access