Design and Simulation of SAW-Driven Drug Delivery Device

This thesis introduces a method of drug delivery system with the application of Surface Acoustic Wave (SAW)-induced acoustic waves in a PDMS microfluidic channel. The surface acoustic waves are generated through applying Alternating Current (AC) on the metal interdigital transducers (IDTs) which are fabricated on the piezoelectrical material substrate. Due to different density and the compressibility of liquid drug, the acoustic waves force that impacts the liquid medium is different. In this thesis, the design and simulations of SAW- driven drug delivery device are presented. The piezoelectrical material is first introduced to explain the phenomenon of a voltage is generated when mechanical stress is applied on piezoelectric material. If an AC voltage is applied on the piezoelectrical material, then a sine wave is generated. COMSOL Multiphysics was used to conduct simulation of this device. Standing Surface Acoustic Wave (SSAW) and Traveling Surface Acoustic Wave (TSAW) are both analyzed in this simulation. Based on the different SAW conditions, the simulation of particle trajectory in microfluidic channel is analyzed in order to demonstrate the SAW impact on liquid.

Author

• Zhou, You

Language

• en

Date created

• 2020

Type of Work

• Master's Thesis

License

• All rights reserved

Rights statement

• In Copyright

GW Unit

• Electrical Engineering

Degree

• M.S.

Advisor

• Zaghloul, Mona E

Committee Member(s)

• Zaghloul, Mona E
• Ahmadi, Shahrokh
• Wu, Jerry

Persistent URL

•  https://scholarspace.library.gwu.edu/etd/2b88qc97p