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  1. Acoustic Vaporization Threshold of Lipid Coated Perfluoropentane Droplets [Download]

    Title: Acoustic Vaporization Threshold of Lipid Coated Perfluoropentane Droplets
    Author: Aliabouzar, Mitra
    Description: Ultrasound has been embraced as a non-invasive, well-understood and relatively inexpensive tool for diagnostic and therapeutic purposes compared to other imaging modalities such as computed tomography, positron emission tomography and magnetic resonance imaging. However, this modality suffers from low sensitivity. To overcome this limitation, ultrasound contrast agents have been introduced which are gas-filled colloidal particles with a size range of 1-7 micrometers. These microbubbles are highly echogenic and therefore they enhance the sensitivity of conventional ultrasound imaging by expansion and contraction in the alternating pressure waves of the ultrasound beam, while tissue is almost incompressible. Currently available microbubbles used for ultrasound imaging and therapeutics are restricted to intravascular space due to their micron size distribution. Recently an interest is developed in designing novel contrast agents with enhanced stability in vivo and a sufficiently small size distribution for extravascular interrogations (Fig.1). Introducing phase-shift droplets which consist of a nanoscale droplet of perfluorocarbons in an encapsulating shell has led to novel ways of approaching ultrasound-based techniques for both diagnostic and therapeutic purposes. These droplets undergo a phase transition to the highly echogenic gaseous state and are convertible to micron-sized bubbles upon the input of sufficient acoustic activation energy which is termed as acoustic droplet vaporization (ADV) [1]-[3]. In this study, we investigated the ADV thresholds and its dependence on excitation pressure and frequency using acoustic recordings. In addition, we have also compared the scattered response from droplets with that of conventional microbubbles at the corresponding excitation pressure and frequency.
    Keywords: Research Days 2018, Ultrasound, Perfluoropentane droplets
    Date Uploaded: 04/28/2018
  2. Sigur Center Asia Report, Issue 36: Taiwan Goes to the Polls: Ramifications of Change at Home and Abroad [Download]

    Title: Sigur Center Asia Report, Issue 36: Taiwan Goes to the Polls: Ramifications of Change at Home and Abroad
    Author: Sigur Center for Asian Studies
    Description: As Taiwan casts votes for a new government in January 2016, the world is watching closely to see how the election might shake up Taipei’s domestic policies and its relationships with neighbors. Polls indicate the Democratic Progressive Party (DPP) candidate, Tsai Ing-wen, has a 2-to-1 lead over the ruling Kuomintang (KMT) and its candidate, Eric Chu, as well as the DPP likely securing a majority in the Legislative Yuan. The KMT is perceived by voters as being pro-China, so the shift in domestic politics driving the probable DPP victory may have profound implications for regional security and economic dynamics, not to mention U.S. foreign policy in East Asia. In this Asia Report, we present the analysis offered at a recent conference – Voting for Change: The Impact of Taiwan’s Upcoming Elections, sponsored by the Sigur Center for Asian Studies.
    Keywords: Sigur Center Asia Report, Sigur Center, ESIA, Elliott School of International Affairs, Asian studies, Asia, Foreign affairs, International affairs, Taiwan, Election, Independence, KMT, DPP, China, Cross-strait
    Date Uploaded: 03/03/2018
  3. Why Don't We Hear from the Women: The Female Voice in Public Settings [Download]

    Title: Why Don't We Hear from the Women: The Female Voice in Public Settings
    Author: Gasteier, Gretchen
    Description:
    Keywords: The Eckles Prize for Freshman Research Excellence
    Date Uploaded: 05/24/2017
  4. 'It is the east': Shakespearean Tragedies in East Asia [Download]

    Title: 'It is the east': Shakespearean Tragedies in East Asia
    Author: Huang, Alexa
    Description: Shakespearean tragedies have played an important part in modern and contemporary East Asian engagements with Western cultures. Japanese, Korean, Chinese, and Singaporean translations, rewritings, films, and theatre productions have three important shared characteristics, namely hybridization of genres, intra-regional and trans-historical allusions, and spirituality. These adaptations tend to present the plays in hybrid performative genres, sometimes turning tragedy into comedy or parody. These adaptations are also informed by intra-regional borrowing and allusions that matter to each separate cultural location and to East Asia as a whole. They tend to interpret Shakespearean tragedies through issues of spirituality and through the artists' personal, rather than national, identities, giving primacy to personal life stories and to the interaction with the audience, rather than attempting 'authentic' representations either of Shakespearean tragedy or indeed of 'Asia'.
    Keywords: East Asian studies, Shakespeare, Globalization, Translation, Adaptation, Spirituality, King Lear, Hamlet, Romeo and Juliet, Film
    Date Uploaded: 10/14/2016
  5. Using Real-time Labor Market Information on a Nationwide Scale [Download]

    Title: Using Real-time Labor Market Information on a Nationwide Scale
    Author: Reamer, Andrew
    Description: This brief examines the potential and limitations of real-time LMI for federal agencies and national trade associations. It finds that real-time LMI offers potential benefits for five activities conducted by these organizations: > Labor market research; > Preparing occupational profiles; > Statistical modeling; > Managing grant programs; and > Delivering constituent services.
    Keywords: Public policy
    Date Uploaded: 11/12/2015
  6. Thin the Soup or Shorten the Line: Washington Area Nonprofits Adapt to Uncertain Times, Working Paper 006 [Download]

    Title: Thin the Soup or Shorten the Line: Washington Area Nonprofits Adapt to Uncertain Times, Working Paper 006
    Author: Atkins, Patricia
    Description: Human services nonprofit organizations are crucial partners to government and the private sector in developing and maintaining healthy communities and families. They are able to leverage multiple funding streams to create a greater capacity to deliver services than any single funding source could achieve on its own. Because they often have strong relationships with the people and neighborhoods where they work, nonprofits are well-positioned to meet community needs. However, in the current economic climate, Washington-area human services nonprofits are being squeezed by rising demand, escalating costs, and increasing administrative tasks, all accompanied by only sluggish revenue growth. An analysis using survey results, tax documents, interviews, and local government budget data finds that these organizations have coped with fiscal stress in a variety of ways—many of which could lead to significant erosion in the quality and quantity of services provided to the community. There are models, though, to bolster nonprofits which should be considered by regional philanthropic organizations and government alike. But overall, the public and private sectors need to work with the nonprofit sector to jointly develop solutions that will meet the needs of community residents without overly burdening the resources of any one sector.
    Keywords: Public policy
    Date Uploaded: 09/28/2015