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Filtering by: Committee Member Tzatsos, Alexandros Author Chatterjee Bhowmick, Diti Type of Work Thesis or Dissertation

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The molecular mechanisms of stress-induced amylin turnover in pancreatic beta cell

Description:

Islet amyloid polypeptide (IAPP) or amylin is a pancreatic hormone produced and co-secreted with insulin from pancreatic islet β-cells that exerts local and system effects in the human body. The human form is a highly amyloidogenic and pathogenic due to its intrinsic property to aggregate in the...

Author:

Chatterjee Bhowmick, Diti

Keyword:

Islet amyloid polypeptide, Type 2 diabetes mellitus, proteasome, protein trafficking, transcription, and amylin

GW Unit:

Biochemistry & Systems Biology

Degree:

Ph.D.

Advisor:

Chiaramello, Anne and Jeremic, Aleksandar M

Committee Member(s):

Donaldson, Julie G, Tzatsos, Alexandros, O’Halloran, Damien, and Donaldson, Robert P

Resource Type:

Thesis or Dissertation