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Filtering by: Advisor Villagra, Alejandro Author John Ephrame, Sophiya

Analysis of the Role of HDAC6 on MITF Pathway, in the Pathogenesis of Melanoma

Description:

The histone deacetylase 6 (HDAC6), which belongs to class IIb family of HDACs is known to play a role in different cellular processes, involved in the pathogenesis of cancer and immune regulation. Recently, we found that treatment of cancer cells with HDAC6 inhibitors (HDAC6is) lead to an...

Author:

John Ephrame, Sophiya

Keyword:

Melanoma, HDAC6, BRAF-resistance, Nexturastat A, Pathways, and MITF

GW Unit:

Biological Sciences

Degree:

M.S.

Advisor:

Villagra, Alejandro

Committee Member(s):

Villagra, Alejandro and Vanderhoek, Jack

Resource Type:

Thesis or Dissertation