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Filtering by: Advisor LaMantia, Anthony-Samuel Type of Work Thesis or Dissertation

Disrupted Mitochondrial Metabolism Alters Cortical Layer II/III Projection Neuron Differentiation

Description:

Mitochondrial metabolism of reactive oxygen species (ROS) is tightly regulated during brain development. Imbalance has been correlated to neuropsychiatric disorders. Nevertheless, the contribution of ROS accumulation to aberrant cortical circuit organization and function remains unknown....

Author:

Fernandez, Alejandra

Keyword:

neuronal differentiation, schizophrenia, mitochondria, neurodevelopment, autism, and oxidative stress

GW Unit:

Biological Sciences

Degree:

Ph.D.

Advisor:

LaMantia, Anthony-Samuel and Maynard, Thomas M

Committee Member(s):

Chiaramello, Anne, Manzini, Chiara, O’Halloran, Damien, and Sockanathan, Shanthini

Resource Type:

Thesis or Dissertation