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Filtering by: Advisor LaMantia, Anthony-Samuel Type of Work Thesis or Dissertation

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Disrupted Mitochondrial Metabolism Alters Cortical Layer II/III Projection Neuron Differentiation

Description:

Mitochondrial metabolism of reactive oxygen species (ROS) is tightly regulated during brain development. Imbalance has been correlated to neuropsychiatric disorders. Nevertheless, the contribution of ROS accumulation to aberrant cortical circuit organization and function remains unknown....

Author:

Fernandez, Alejandra

Keyword:

neurodevelopment, mitochondria, autism, oxidative stress, schizophrenia, and neuronal differentiation

GW Unit:

Biological Sciences

Degree:

Ph.D.

Advisor:

Maynard, Thomas M and LaMantia, Anthony-Samuel

Committee Member(s):

Sockanathan, Shanthini, Chiaramello, Anne, Manzini, Chiara, and O’Halloran, Damien

Resource Type:

Thesis or Dissertation